4-Androstenediol
The conversion rate is about 15.76%, almost triple that of 4-androstenedione, due to utilization of a different enzymatic pathway.[1] However, due to its lower intrinsic activity in comparison, in the presence of full agonists like testosterone or dihydrotestosterone (DHT), 4-androstenediol has antagonistic actions, behaving more like an antiandrogen.It has approximately 0.5% and 0.6% of the affinity of estradiol at the ERα and ERβ, respectively.[2] Patrick Arnold holds a 1999 patent on "Use of 4-androstenediol to increase testosterone levels in humans".You can help Wikipedia by expanding it.This drug article relating to the genito-urinary system is a stub.