8,9-Dehydroestrone

8,9-Dehydroestrone, or Δ8-estrone, also known as estra-1,3,5(10),8-tetraen-3-ol-17-one, is a naturally occurring estrogen found in horses which is closely related to equilin, equilenin, and estrone, and, as the 3-sulfate ester sodium salt, is a minor constituent (3.5%) of conjugated estrogens (Premarin).[1][2][3][4] It produces 8,9-dehydro-17β-estradiol as an important active metabolite, analogously to conversion of estrone or estrone sulfate into estradiol.[6][3] In addition to 8,9-dehydroestrone and 8,9-dehydro-17β-estradiol, 8,9-dehydro-17α-estradiol is likely also to be present in conjugated estrogens, but has not been identified at this time.This article about a steroid is a stub.You can help Wikipedia by expanding it.This drug article relating to the genito-urinary system is a stub.
Routes ofadministrationBy mouthDrug classEstrogenIUPAC nameCAS NumberChemSpiderCompTox DashboardFormulaMolar massSMILESnaturally occurringhorsesequilinequileninestronesulfatesodiumconjugated estrogens8,9-dehydro-17β-estradiolactive metaboliteestrone sulfateestradiolEstrogensantiestrogensAlfatradiolandrogensanabolic steroidstestosteronemethyltestosteronemetandienoneprogestinsnorethisteronenoretynodreletynodiol diacetatetiboloneClomestroneCloxestradiol acetateConjugated estriolEpiestriolEpimestrolEsterified estrogensEstetrolestradiol acetateestradiol benzoateestradiol cypionateestradiol enanthateestradiol undecylateestradiol valeratepolyestradiol phosphateestradiol ester mixturesClimacteronEstramustine phosphateEstriolestriol succinatepolyestriol phosphateEstrogenic substancesEstropipate (piperazine estrone sulfate)EthinylestradiolEthinylestradiol sulfonateHydroxyestrone diacetateMestranolMethylestradiolMoxestrolNilestriolPrasterone (dehydroepiandrosterone; DHEA)Prasterone enanthatePrasterone sulfatePromestrieneQuinestradolQuinestrolBenzestrolBifluranolChlorotrianiseneDienestrolDienestrol diacetateDiethylstilbestrol (stilbestrol)Dimestrol (diethylstilbestrol dimethyl ether)Fosfestrol (diethylstilbestrol diphosphate)Mestilbol (diethylstilbestrol monomethyl ether)Doisynoestrol (fenocycline)HexestrolMethallenestrilMethestrol (promethestrol)Methestrol dipropionate (promethestrol dipropionate)ParoxypropioneQuadrosilanTriphenylbromoethyleneTriphenylchloroethyleneZeranolProgonadotropinsAntiandrogensbicalutamideGnRH agonistsGnRH (gonadorelin)leuprorelinGonadotropinsAcolbifeneAnordrinBazedoxifeneBroparestrolClomifeneCyclofenilEnclomifeneEpitiostanolLasofoxifeneMepitiostaneOrmeloxifeneOspemifeneRaloxifeneTamoxifenToremifeneElacestrantFulvestrantTrilostaneAromatase inhibitorsAminoglutethimideTestolactoneFadrozoleFormestaneAnastrozoleExemestaneLetrozoleAntigonadotropinsoxandrolonefluoxymesteroneD2 receptorantagonistsprolactindomperidonemetoclopramiderisperidonehaloperidolchlorpromazinesulpiridegoserelinGnRH antagonistscetrorelixelagolixProgestogenschlormadinone acetatecyproterone acetategestonorone caproatehydroxyprogesterone caproatemedroxyprogesterone acetatemegestrol acetateDanazolGestrinoneAndrovax (androstenedione albumin)Ovandrotone albumin (Fecundin)WHO-EMWithdrawnClinical trialsList of estrogensEstrogen receptormodulators2-Hydroxyestradiol2-Hydroxyestrone3-Methyl-19-methyleneandrosta-3,5-dien-17β-ol3α-Androstanediol3α-Hydroxytibolone3β-Hydroxytibolone3β-Androstanediol4-Androstenediol4-Androstenedione4-Fluoroestradiol4-Hydroxyestradiol4-Hydroxyestrone4-Methoxyestradiol4-Methoxyestrone5-Androstenediol7-Oxo-DHEA7α-Hydroxy-DHEA7α-Methylestradiol7β-Hydroxyepiandrosterone8,9-Dehydroestradiol8β-VE210β,17β-Dihydroxyestra-1,4-dien-3-one (DHED)11β-Chloromethylestradiol11β-Methoxyestradiol15α-Hydroxyestradiol16-Ketoestradiol16-Ketoestrone16α-Fluoroestradiol16α-Hydroxy-DHEA16α-Hydroxyestrone16α-Iodoestradiol16α-LE216β-Hydroxyestrone16β,17α-Epiestriol (16β-hydroxy-17α-estradiol)17α-Estradiol17α-Dihydroequilenin17α-Dihydroequilin17α-Epiestriol (16α-hydroxy-17α-estradiol)17α-Ethynyl-3α-androstanediol17α-Ethynyl-3β-androstanediol17β-Dihydroequilenin17β-Dihydroequilin17β-Methyl-17α-dihydroequileninAbirateroneAbiraterone acetateAlestramustineAlmestronemetandienone (methandrostenolone)nandroloneAtrimustineBolandiolBolandiol dipropionateButolameCloxestradiolCyclodiolCyclotriolDHEA-Sent-EstradiolEpiestriol (16β-epiestriol, 16β-hydroxy-17β-estradiol)ERA-63 (ORG-37663)Lipoidal estradiolEstramustineEstrapronicateEstrazinolEstrofurateEstromustineEstrone methyl etherEstropipateEtamestrol (eptamestrol)EthinylandrostenediolEthandrostateEthinylestradiol 3-benzoateEthinylestriolEthylestradiolEtynodiolHexolameHippulinLynestrenolLynestrenol phenylpropionateMytatrienediolOrestratePentolameProdiameProlameRU-16117(R,R)-THC(S,S)-THC2,8-DHHHCβ-LGND2 (GTx-878)AllenestrolAllenolic acidBisdehydrodoisynolic acidButestrolCarbestrolD-15414DCW234DiarylpropionitrileDiethylstilbestrolDimestrol (dianisylhexene)DimethylstilbestrolDoisynolic acidEfavirenzERB-196 (WAY-202196)Erteberel (SERBA-1, LY-500307)Estrobin (DBE)FenestrelFERb 033Furostilbestrol (diethylstilbestrol difuroate)GTx-758ICI-85966 (Stilbostat)meso-Butestrolmeso-HexestrolMestilbolMethestrolMethestrol dipropionatePentafluranolPhenestrolPrinaberel (ERB-041, WAY-202041)PropylpyrazoletriolSC-4289SERBA-2SKF-82,958TerfluranolTriphenyliodoethyleneTriphenylmethylethylene (triphenylpropene)WAY-166818WAY-200070WAY-204688 (SIM-688)WAY-214156ERB-26ERA-45ERB-79ZK-283197anetholedianetholedianolphotoanetholeChalconoidsisoliquiritigeninphloretinphlorizin (phloridzin)wedelolactoneCoumestanscoumestrolpsoralidinFlavonoids7,8-DHF8-prenylnaringeninapigeninbaicaleinbaicalinbiochanin AcalycosincatechindaidzeindaidzinepicatechinformononetinglabreneglabridingenisteingenistinglyciteinkaempferolliquiritigeninmirificinmyricetinnaringeninpinocembrinprunetinpuerarinquercetintectoridintectorigeninLavender oilLignansenterodiolenterolactonenyasol (cis-hinokiresinol)MetalloestrogenscadmiumPesticidesalternarioldieldrinendosulfanfenarimolmethiocarbmethoxychlortriclocarbantriclosanPhytosteroidsdigitoxindigitalisdiosgeninguggulsteronePhytosterolsβ-sitosterolcampesterolstigmasterolResorcylic acid lactoneszearalanoneα-zearalenolβ-zearalenolzearalenonezeranol (α-zearalanol)taleranol (teranol, β-zearalanol)SteroiddeoxymiroestrolmiroestrolStilbenoidsresveratrolrhaponticinSynthetic xenoestrogensalkylphenolsbisphenolsparabensphthalatesagnuside2-Phenylbenzofuran4'-Hydroxynorendoxifen27-HydroxycholesterolAcefluranolAfimoxifeneAnordiolArzoxifeneBrilanestrantCamizestrantClomifenoxideDesmethylchlorotrianiseneDroloxifeneEndoxifenEtacstil (GW-5638, DPC-974)Ethamoxytriphetol (MER-25)FemarelleFispemifeneICI-55548IdoxifeneLevormeloxifeneLN-1643LN-2299MenerbaMiproxifeneMiproxifene phosphateNafoxidineNitromifeneNNC 45-0095PanomifenePipendoxifeneRimostil (P-081)SpironolactoneTAS-108 (SR-16234)TrioxifeneZindoxifeneZuclomifene7β-Hydroxy-DHEACytestrol acetateFulvestrant (ICI-182780)GlyceollinsICI-164384MethylepitiostanolMethylpiperidinopyrazolePhenytoinProchlorazERX-112-MethoxyestradiolAfimoxifene (4-hydroxytamoxifen)AldosteroneAtrazineBisphenol Ap,p'-DDTHydroxytyrosolKeponeNicotinic acidNicotinamideNonylphenolOleuropeingenito-urinary system