Golden rice

In 2016, 107 Nobel laureates wrote an open letter to Greenpeace and its supporters, asking them to abandon their campaign against genetically modified crops in general and golden rice in particular.[6] In 2024, the Filipino Court of Appeals issued a cease and desist order for the growth of golden rice in the country, citing a lack of scientific certainty regarding its health and environmental impact.[10] The scientific details of the rice were first published in 2000, the product of an eight-year project by Ingo Potrykus of the Swiss Federal Institute of Technology and Peter Beyer of the University of Freiburg.[21] On 17 April 2024, the Court of Appeals in the Philippines issued a cease-and-desist order on the commercial propagation of two genetically modified crops, golden rice and Bt eggplant, citing a lack of "full scientific certainty" regarding their health and environmental impact.The decision was in response to a petition filed by groups including Magsasaka at Siyentipiko para sa Pag-unlad Agrikultura (Masipag) and Greenpeace Southeast Asia.Recent analysis has shown the plant's endogenous enzymes process the lycopene to beta-carotene in the endosperm, giving the rice the distinctive yellow colour for which it is named.Between 1990 and 2013, more than 40 efficacy studies of VAS in children 6–59 months of age were conducted, and two systematic reviews and meta-analyses have concluded that VA supplements can considerably reduce mortality and morbidity during childhood.Moreover, this claim referred to an early cultivar of golden rice; one bowl of the latest version provides 60% of Recommended Dietary Allowance (RDA) for healthy children.[40] Other groups argued that a varied diet containing foods rich in beta-carotene such as sweet potato, leaf vegetables and fruit would provide children with sufficient vitamin A.[41] However, Keith West of Johns Hopkins Bloomberg School of Public Health has said that foodstuffs containing vitamin A are often unavailable, only available in certain seasons, or are too expensive for poor families to obtain.[31] The study, involving feeding GM rice to children from 6 to 8 years old in China, was later found to have violated human research rules of both Tufts University and the federal government."[50] This marks the fourth national health organisation to approve the use of golden rice in 2018, joining Australia, Canada and New Zealand who issued their assessments earlier in the year.[28][44][53] British author Mark Lynas reported in Slate that the vandalism was carried out by a group of activists led by Kilusang Magbubukid ng Pilipinas (KMP) (literally 'Farmers' Movement of the Philippines').
A simplified overview of the carotenoid biosynthesis pathway in golden rice. The enzymes expressed in the endosperm of golden rice, shown in red, catalyse the biosyntheis of beta-carotene from geranylgeranyl diphosphate . Beta-carotene is assumed to be converted to retinal and subsequently retinol (vitamin A) in the animal gut.
Prevalence of vitamin A deficiency. Red is most severe (clinical), green least severe. Countries not reporting data are coded blue. Data collected for a 1995 report.
African riceYellow ricewhite riceSpeciesOryza sativaCultivarRockefeller Foundationgenetic engineeringbiosynthesizebeta-carotenevitamin Afortified foodshortage of dietary vitamin AInternational Rice Research InstituteBill & Melinda Gates Foundationenvironmentalanti-globalisationgenetically modified cropsFilipino Court of Appealscease and desist ordercarotenoidenzymesendospermgeranylgeranyl diphosphateretinolPeter Bramleyphytoene desaturaselycopenephytoeneGM tomatocaroteneendogenouscyclaseIngo PotrykusSwiss Federal Institute of TechnologyPeter BeyerUniversity of FreiburgLouisiana State UniversityPhilippinesTaiwanBangladeshgreenhouseHealth CanadaFood and Drug Administrationallergiesprovitamin Acountry's Supreme Courtagriculture departmentWrit of KalikasanCourt of Appeals in the PhilippinesBt eggplantGreenpeace Southeast AsiaUniversity of the Philippines Los BañosPhilippine Rice Research Institutetransformingphytoene synthasedaffodilNarcissus pseudonarcissusErwinialycopene cyclasepromoterexpressedtransit peptideplastidSyngentaVitamin A deficiencystaple foodgenetic modificationhydrophobicRecommended Dietary Allowanceclinical trialAmerican Society for NutritionGenetically modified food controversiesGreenpeacegenetically modified organismsVandana ShivaIndianbiodiversitysweet potatoleaf vegetablesJohns Hopkins Bloomberg School of Public HealthMichael PollanThe American Journal of Clinical NutritionTufts Universityethics review boardBill and Melinda Gates FoundationNobel laureatesProceedings of the National Academy of Sciences of the United States of AmericaMark LynassubsistencefarmersFree licensesMonsanto CompanyBibcodeBusinessWorldThe Boston GlobeRevkin, AndrewQiu, JaneHistory of rice cultivationAsian riceVarietiesAdamchini ChawalAjara Ghansal riceAmbemoharAndaman Karen MusleyArborio riceArunachal Pradesh Khaw Tai (Khamti Rice)Balaghat ChinnorBhandara ChinoorBasmatiBhutanese red riceBomba riceBoka ChaulBora saulCalasparra riceCalrose riceCamargue red riceCarnaroliChampa riceChak-Hao (Black rice)Chokuwa saulDubraj riceGobindobhogJapanese riceJaponica riceJasmatiJasmine riceJeeraphoolJoha riceKalonuniaKoraput KalajeeraKoshihikariMaratelliMarchaMatta riceMolakolukuluMushqbudjiNàng Thơm Chợ Đào riceNavara riceNishiki ricePatna ricePaw hsan hmwePokkaliPonni ricePusa Basmati 1121Red Cargo riceRiceberrySasanishikiSemi-dwarf IR36Sona masuri riceTulaipanjiUttarakhand Lal ChawalVialone NanoWayanad GandhakasalaWayanad JeerakasalaWehani riceYamada NishikiCarolina GoldNew Rice for AfricaAromatic riceHybrid ricePerennial riceGlutinous riceWeedy riceFlattened ricePuffed riceBroken riceBrown riceRed riceBlack riceGerminated brown riceParboiled riceArroz con polloAsopaoBiryaniChamporadoCongeeGimbapLampraisMexican ricePaellaRisottoTahchinTuwon shinkafaMaize/cornMON 810MON 863List of varieties of genetically modified maize/cornPotatoAmfloraSoybeanRoundup ready soybeanVistive GoldTomatoFlavr SavrBt cottonArabidopsisBrinjalCanolaSmartStaxSugar beetMustardAnimalsMammalsKnockout mouseOncomouseEnviropigHerman the BullKnockout ratRabbitInsectsGloFishSalmonBacteriavirusesIce-minus bacteriaHepatitis B vaccineOncolytic virusProcessesInserting DNAAgrobacteriaBiolisticsElectroporationGenetic transductionLipofectionMicroinjectionSomatic cell nuclear transferTransfectionRecombinant DNATransgenesisCisgenesisGenetically modified foodControversiesPharmingDow AgroSciencesDuPont PioneerMonsantohumansGene therapyGenetic enhancementGenetic testingGene knockoutGene knockdownGene targetingTransgeneDetection of genetically modified organismsGenetic pollutionGenetics in fictionHuman enhancementReverse transfectionTranshumanismGenetic use restriction technologyRegulationCartagena Protocol on BiosafetyEuropeAfricaNorth AmericaSouth AmericaOceaniaEugenicsCloningStem cell researchSynthetic biologyBiologyGeneticsBiotechnologyBioethics