21-Hydroxypregnenolone
21-Hydroxypregnenolone, also known as prebediolone, as well as 3β,21-dihydroxypregn-5-en-20-one, is a naturally occurring and endogenous pregnane steroid, and an intermediate in the biosynthesis of 11-deoxycorticosterone (21-hydroxyprogesterone), corticosterone (11β,21-dihydroxyprogesterone), and other corticosteroids.[1] It is formed from pregnenolone in the adrenal glands.[1] The 21-acetate ester of 21-hydroxypregnenolone, prebediolone acetate, is described as a glucocorticoid and has been used in the treatment of rheumatoid arthritis.This article about a steroid is a stub.You can help Wikipedia by expanding it.
IUPAC nameCAS NumberChEMBLChemSpiderPubChemCompTox DashboardSMILESChemical formulaMolar massstandard statenaturally occurringendogenouspregnanesteroidintermediatebiosynthesis11-deoxycorticosteronecorticosteronecorticosteroidspregnenoloneadrenal glandsacetateprebediolone acetateglucocorticoidrheumatoid arthritis17α-HydroxypregnenoloneProgesterone17α-HydroxyprogesteroneHuman Metabolome Database, HMDBsteroidsPrecursorsCholesterol22R-Hydroxycholesterol20α,22R-DihydroxycholesterolGlucocorticoids3α,5α-Tetrahydrocorticosterone5α-Dihydrocorticosterone11-Deoxycortisol11-Ketoprogesterone21-Deoxycortisol21-DeoxycortisoneCortisolCortisone5α-DihydrocortisolMineralocorticoids5α-Dihydroaldosterone11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)11β-Hydroxyprogesterone (21-deoxycorticosterone)18-Hydroxy-11-deoxycorticosterone18-HydroxycorticosteroneAldosteroneSex steroidsAndrogens11-Ketodihydrotestosterone11-Ketotestosterone7β-Hydroxyepiandrosterone11β-HydroxyandrostenedioneAdrenosterone (11-ketoandrostenedione)AndrostenediolAndrostenedioneAndrosteroneDehydroandrosteroneDHEA sulfateDihydrotestosteroneEpiandrosteroneEpitestosterone16α-Hydroxyandrostenedione16α-Hydroxy-DHEA16α-Hydroxy-DHEA sulfateTestosterone3α-Androstanediol3α-Androstanediol glucuronide3β-Androstanediol5β-Dihydrotestosterone3α-Etiocholanediol3β-EtiocholanediolAndrostenediol sulfateAndrostenetriolAndrosterone glucuronideAndrosterone sulfateEtiocholanedioneEtiocholanoloneEtiocholanolone glucuronideEpietiocholanoloneTestosterone glucuronideTestosterone sulfateEstrogensEstetrolEstradiolEstroneEstriol17α-Estradiol16β-Epiestriol (16β-hydroxyestradiol)17α-Epiestriol (16α-hydroxy-17α-estradiol)16β,17α-Epiestriol (16β-hydroxy-17α-estradiol)2-Hydroxyestradiol2-Hydroxyestriol2-Hydroxyestrone4-Hydroxyestradiol4-Hydroxyestriol4-Hydroxyestrone4-Methoxyestradiol4-Methoxyestrone16α-Hydroxyestrone16β-Hydroxyestrone16-Ketoestradiol16-Ketoestrone27-Hydroxycholesterol4-Androstenedione5-Androstenediol7-Keto-DHEA7α-Hydroxy-DHEA2-Methoxyestradiol2-Methoxyestrone2-Methoxyestriol4-MethoxyestriolEstradiol disulfateEstradiol glucuronideEstradiol 3-glucuronideEstradiol 3-glucuronide 17β-sulfateEstradiol sulfateEstradiol 17β-sulfateEstrone glucuronideEstrone sulfateEstriol glucuronideEstriol sulfate