Oxyphencyclimine
Oxyphencyclimine is a muscarinic receptor antagonist, given orally to treat peptic ulcer disease and gastrointestinal spasms.It has antispasmodic and antimotility properties.The reaction of chloroacetonitrile (1) with methanol and hydrogen chloride leads to the corresponding iminoether (Pinner reaction).Displacement of the halogen with the sodium salt 5 affords oxyphencyclimine (6).This drug article relating to the gastrointestinal system is a stub.
Drugs.comATC codeA03AA01IUPAC nameCAS NumberIUPHAR/BPSChemSpiderChEMBLCompTox DashboardECHA InfoCardFormulaMolar massmuscarinic receptor antagonistpeptic ulcer diseasespasmsantispasmodicantimotilitychloroacetonitrilemethanolhydrogen chloridePinner reactiontetrahydropyrimidineCharles Pfizer & Co. Inc.functional gastrointestinal disordersfunctional bowel disordersAntimuscarinicsCamylofinDicycloverineDifemerineDihexyverineMebeverinePiperidolateRociverineTrimebutineQuaternary ammoniumBenziloneBevoniumDiphemanilFenpiveriniumGlycopyrroniumHexocycliumIsopropamideMepenzolateMethanthelineOtiloniumOxyphenoniumPenthienatePipenzolatePoldinePrifiniumPropanthelineTiemoniumTimepidiumTridihexethylPhosphodiesterase inhibitorsDrotaverineMoxaverinePapaverineserotonin receptors5-HT3 antagonistsAlosetronCilansetron5-HT4 agonistsMosaprideAlverineCaroverineChlorbenzoxamineDiisopromineDimethylaminopropionylphenothiazineFenoverineFenpipraneIdanpramineIsomethepteneMentha piperitaPhloroglucinolPinaverium bromideProxazoleSimeticoneTiropramideTrepibutoneTrimethyldiphenylpropylamineBelladonnaAtropineHyoscyamineScopolamineButylscopolamineMethylscopolamineCimetropium bromideFentonium bromideMethylatropinePropulsivesPrimarily dopamine antagonistsAlizaprideBromoprideCleboprideDomperidoneMetoclopramideCinitaprideCisaprideAcotiamideMuscarinic acetylcholine receptormodulatorsmAChRsAgonists77-LH-28-1AceclidineAcetylcholineAlvamelineArecolineBethanecholButyrylcholineCarbacholCevimelineCholinecis-DioxolaneClozapineDesmethylclozapine (norclozapine)ItamelineMethacholineMilamelineMuscarineOxotremorinePilocarpineSabcomelineTalsaclidineTazomeline