4-DAMP
4-DAMP (1,1-dimethyl-4-diphenylacetoxypiperidinium iodide) is a selective muscarinic acetylcholine receptor (mAChR) M3 antagonist.[2] It is also able to antagonize M1 receptors but has preferential activity at the M3 receptor.[3][4] It competitively binds to the acetylcholine binding site on mAChRs, causing right-ward shift in the dose response curves for mAChR agonists.This article about an organic compound is a stub.You can help Wikipedia by expanding it.
Preferred IUPAC nameCAS NumberChemSpiderPubChemCompTox DashboardSMILESChemical formulaMolar massstandard stateselectivemuscarinic acetylcholine receptorantagonistM1 receptorsSigma-AldrichmodulatorsmAChRsAgonists77-LH-28-1AceclidineAcetylcholineAlvamelineArecolineBethanecholButyrylcholineCarbacholCevimelineCholinecis-DioxolaneClozapineDesmethylclozapine (norclozapine)ItamelineMethacholineMilamelineMuscarineOxotremorinePilocarpineSabcomelineTalsaclidineTazomelineVedaclidineVU-0152099VU-0152100VU-0238429XanomelineAntagonists3-Quinuclidinyl benzilateAclidinium bromide+formoterolAbediterolAF-DX 384Ambutonium bromideAnisodamineAnisodineAntihistamines (first-generation)brompheniraminebuclizinecaptodiamechlorphenamine (chlorpheniramine)cinnarizineclemastinecyproheptadinedimenhydrinatedimetindenediphenhydraminedoxylaminemeclizinemequitazineperlapinephenindaminepheniraminephenyltoloxaminepromethazinepropiomazinetriprolidineAtropineAtropine methonitrateAtypical antipsychoticsfluperlapineolanzapine+fluoxetinequetiapinetenilapinezotepineBenactyzineBenzatropine (benztropine)BenziloneBenzilylcholine mustardBenzydamineBevoniumBiperidenBornaprineCamylofinCAR-226,086CAR-301,060CAR-302,196CAR-302,282CAR-302,668CaramiphenCimetropium bromideClidinium bromideCloperastineCS-27349CyclobenzaprineCyclopentolateDarifenacinDesfesoterodineDexetimideDicycloverine (dicyclomine)DihexyverineDifemerineDiphemanil metilsulfateDitranDrofenineEA-3167EA-3443EA-3580EA-3834Emepronium bromideEtanautineEtybenzatropine (ethybenztropine)FenpiveriniumFentonium bromideFesoterodineFlavoxateGlycopyrronium bromide+beclometasone/formoterol