Stevia
[12] The genus was named for the Spanish botanist and physician Pedro Jaime Esteve (Petrus James Stevus, 1500–1556) a professor of botany at the University of Valencia.[13] In 1899, Swiss botanist Moisés Santiago Bertoni, while conducting research in eastern Paraguay, first described the plant and the sweet taste in detail.[19][6]: 60 In December 2008, the FDA gave a "no objection" approval for GRAS status to Truvia[a] and PureVia,[b] both of which use rebaudioside A derived from the Stevia rebaudiana plant.[27][28] In May 2008, Coca-Cola and Cargill announced the availability of Truvia, a consumer-brand Stevia sweetener containing erythritol and Rebiana,[29] which the FDA permitted as a food additive in December 2008.[45] A 2010 review found that the use of Stevia rebaudiana sweeteners as replacements for sugar might benefit children, people with diabetes, and those wishing to lower their intake of calories.[46] Although both steviol and rebaudioside A have been found to be mutagenic in laboratory in vitro testing,[47] these effects have not been demonstrated for the doses and routes of administration to which humans are exposed.[51][52] The WHO's Joint Experts Committee on Food Additives has approved, based on long-term studies, an acceptable daily intake of steviol glycoside of up to 4 mg/kg of body mass.[47] In August 2019, the US FDA placed an import alert on Stevia leaves and crude extracts – which do not have GRAS status – and on foods or dietary supplements containing them due to concerns about safety and potential for toxicity.