Lycorine
Lycorine is found in different species of Amaryllidaceae which include flowers and bulbs of daffodil, snowdrop (Galanthus) or spider lily (Lycoris).[3] There is currently very little known about the mechanism of action of lycorine, although there have been some tentative hypotheses advanced concerning the metabolism of the alkaloid, based on experiments carried out upon beagle dogs.Presently, it serves some interest in the study of certain yeasts, the principal organism on which lycorine is tested.[10] In a study of dosage used on beagle dogs, the first sign of nausea was observed at as little of a dose of 0.5 mg/kg and occurred within a 2.5 hour span.[13] Lycorine has been seen to have promising biological and pharmacological activities such as antibacterial, antiviral, or anti-inflammatory effects and may have anticancer properties.
IUPAC nameCAS NumberChEMBLChemSpiderECHA InfoCardPubChemCompTox DashboardSMILESChemical formulaMolar massstandard statecrystallinealkaloidAmaryllidaceaeClivia miniataLycorisNarcissusbeagleprotein synthesisascorbic acidbiosynthesisyeastsacetylcholinesterasecytostaticcytoskeletonapoptosisonionsemesisnauseavomitingdiarrheaconvulsionsBibcodeAcetylcholinemetabolismtransportmodulatorsEnzymeInhibitorsAldicarbAminocarbBendiocarbCarbarylCarbendazimCarbofuranCarbosulfanDimetilanEthienocarbEthiofencarbFenobucarbFormetanateFormparanateMethiocarbMethomylMetolcarbMiotineOxamylPirimicarbPromecarbPropamocarbPropoxurThiofanoxDistigmineNeostigmine+glycopyrronium bromidePhenserinePhysostigminePyridostigmineRivastigmineAcotiamideAmbenoniumCaffeineDonepezilEA-3990EA-4056EdrophoniumGalantamineHuperzine AHuprine XIpidacrineItoprideLadostigilMinaprineOctamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide)T-1123T-1152T-1194TL-599TL-1238Tacrine2-Ethoxycarbonyl-1-methylvinyl cyclohexyl methylphosphonateAcephateArmineAzinphos-ethylAzinphos-methylBAY-29952BensulideCadusafosCarbophenothionChlorethoxyfosChlorfenvinphosChlorpyrifosChlorpyrifos-methylCoumaphosCrotylsarinCyanophosCyclosarin (GF)DemephionDemetonDemeton-S-methylDialiforDiazinonDichlorvosDicrotophosDicyclohexyl phosphorofluoridateDiisopropylphosphateDiisopropyl fluorophosphateDimefoxDimethoateDimethyl 4-(methylthio)phenyl phosphateDioxathionDisulfotonEA-2012EA-2054EA-2098EA-2192