Imidazol-4-one-5-propionic acid
It is a colorless compound that is sensitive to light in air.[1] It arises via the action of urocanase on urocanic acid.Hydrolysis of the heterocycle to the glutamic acid derivative is catalyzed by imidazolonepropionate hydrolase.Microbial production of imidazol-4-one-5-propionic acid in the human gut has been shown to affect insulin signaling, which is relevant to type II diabetes.This article about a heterocyclic compound is a stub.
IUPAC nameCAS NumberChemSpiderPubChemCompTox DashboardSMILESChemical formulaMolar massstandard statehistidineimidazoloneurocanaseurocanic acidheterocycletype II diabetesFormiminoglutamic acidUrocanateUrocanate hydrataseAmino acidmetabolismmetabolic intermediatesacetyl-CoAlysineSaccharopineAllysineα-Aminoadipic acid2-Oxoadipic acidGlutaryl-CoAGlutaconyl-CoACrotonyl-CoAβ-Hydroxybutyryl-CoAleucineβ-Hydroxy β-methylbutyric acidβ-Hydroxy β-methylbutyryl-CoAIsovaleryl-CoAα-Ketoisocaproic acidβ-Ketoisocaproic acidβ-Leucineβ-Methylcrotonyl-CoAβ-Methylglutaconyl-CoAβ-Hydroxy β-methylglutaryl-CoAtryptophanalanineN′-FormylkynurenineKynurenineAnthranilic acid3-Hydroxykynurenine3-Hydroxyanthranilic acid2-Amino-3-carboxymuconic semialdehyde2-Aminomuconic semialdehyde2-Aminomuconic acidpyruvatecitrateglycineserine3-Phosphoglyceric acidcreatineGlycocyaminePhosphocreatineCreatinineglutamateα-ketoglutarateGlutamate-1-semialdehydeproline1-Pyrroline-5-carboxylic acidarginineAgmatineOrnithineCitrullineCadaverinePutrescinecysteineglutathioneγ-Glutamylcysteinepropionyl-CoAsuccinyl-CoAvalineα-Ketoisovaleric acidIsobutyryl-CoAMethacrylyl-CoA3-Hydroxyisobutyryl-CoA3-Hydroxyisobutyric acid2-Methyl-3-oxopropanoic acidisoleucine2,3-Dihydroxy-3-methylpentanoic acid2-Methylbutyryl-CoATiglyl-CoA2-Methylacetoacetyl-CoAmethionineS-Adenosyl methionineS-Adenosyl-L-homocysteineHomocysteineCystathionineα-Ketobutyric acidthreonineMethylmalonyl-CoAfumaratephenylalaninetyrosine4-Hydroxyphenylpyruvic acidHomogentisic acid4-Maleylacetoacetic acidoxaloacetateurea cycleCysteine metabolismCysteine sulfinic acidheterocyclic compound