Hippocampal sulcus

During human fetal development, the hippocampal sulcus first appears at approximately 10 weeks of gestational age.At this stage it exists as a broad shallow fissure along the surface of the dentate gyrus.After about 18 weeks, the walls of the fissure fold into each other and begin to fuse.By 30 weeks, the hippocampal sulcus is normally obliterated except for its most medial part, leaving a shallow surface indentation.[1] Enlargement of the hippocampal sulcus has been associated with medial temporal lobe atrophy occurring in Alzheimer's disease.
Hippocampal sulcus remnants seen on T2-weighted axial MRI image.
NeuroNamesNeuroLexAnatomical terms of neuroanatomysulcusdentate gyrussubiculumhippocampusfetal developmentgestational agecornu ammonistemporal lobeatrophyAlzheimer's diseaseHippocampus anatomyNeuroscience Information Frameworkcerebral cortexhuman brainFrontal lobePrefrontalSuperior frontal gyrusMiddle frontal gyrusInferior frontal gyrusPars orbitalisBroca's areaPars opercularisPars triangularisSuperior frontal sulcusInferior frontal sulcusPrecentralPrecentral gyrusPrecentral sulcusMedial frontal gyrusParaterminal gyrusParaolfactory areaStraight gyrusOrbital gyriOrbitofrontal cortexVentromedial prefrontal cortexSubcallosal areaOlfactory sulcusOrbital sulcusParacentral lobuleParacentral sulcusPrimary motor cortexPremotor cortexSupplementary motor areaSupplementary eye fieldFrontal eye fieldsParietal lobeSuperior parietal lobuleInferior parietal lobuleSupramarginal gyrusAngular gyrusParietal operculumIntraparietal sulcusPrecuneusMarginal sulcusPostcentral gyrusPrimary somatosensory cortex3, 1 and 2Secondary somatosensory cortexPosterior parietal cortexOccipital lobeOccipital gyriLateral occipital gyrusLunate sulcusTransverse occipital sulcusVisual cortexCuneusLingual gyrusCalcarine sulcusTransverse temporal gyrusAuditory cortex41 and 42Superior temporal gyrusWernicke's areaPlanum temporaleSuperior temporal sulcusMiddle temporal gyrusOccipitotemporal sulcusFusiform gyrusMedial temporal lobeInferior temporal sulcusInferior temporal gyrusInterlobarsulci/fissuresCentral (frontal+parietal)Lateral (frontal+parietal+temporal)Parieto-occipitalPreoccipital notchLongitudinal fissureCingulate (frontal+cingulate)Collateral (temporal+occipital)Callosal sulcusLimbic lobeParahippocampal gyrusEntorhinal cortexPerirhinal cortexPostrhinal cortexPosterior parahippocampal gyrusPrepyriform areaCingulate cortexSubgenual areaAnterior cingulatePosterior cingulateIsthmus of cingulate gyrusRetrosplenial cortexHippocampal formationFimbria of hippocampusRhinal sulcusIndusium griseumAmygdalaInsular cortexOperculumBrodmann areas