GDF10

[5] GDF10 belongs to the transforming growth factor beta superfamily that is closely related to bone morphogenetic protein-3 (BMP3).[5][6] GDF10 is also known as BMP-3b, with GDF10 and BMP3 regarded as a separate subgroup within the TGF-beta superfamily.[5] In mice, GDF10 mRNA is abundant in the brain, inner ear, uterus, prostate, neural tissues, blood vessels and adipose tissue with low expression in spleen and liver.It is also present in bone of both adults and neonatal mice.[5] Human GDF10 mRNA is found in the cochlea and lung of foetuses, and in testis, retina, pineal gland, and other neural tissues of adults.
AliasesHomoloGeneGeneCardsChromosome 10 (human)RNA expressionGene ontologyOrthologsEntrezEnsemblUniProtPubMedWikidataproteintransforming growth factor beta superfamilybone morphogenetic proteinmorphogenesisinner earuterusprostateneural tissuesblood vesselsadipose tissuespleenneonatalfoetusestestisretinapineal glandBibcodeCell signalingTGFβ signaling pathwayTGF beta superfamily of ligandsTGF beta familyTGF-β1TGF-β2TGF-β3Activin and inhibinBone morphogenetic proteinsGrowth differentiation factorsMyostatin/GDF8Anti-müllerian hormoneTGF beta receptorsActivinfamilyActivin type 1 receptorsACVR1BACVR1CACVRL1BMPR1ABMPR1BActivin type 2 receptorsACVR2AACVR2BbetaglycanTransducersR-SMADI-SMADCerberusChordinDecorinFollistatinGremlinNogginCoreceptorsCriptoTGFβ receptor superfamilymodulatorsALK1 (ACVRL1)Avotermin2 (BMP9)AscrinvacumabDalanterceptALK2 (ACVR1A)AMH (MIS)Eptotermin alfaALK3 (BMPR1A)Dibotermin alfaALK4 (ACVR1B)11 (BMP11)Myostatin (GDF8)InhibinSB-431542ALK5 (TGFβR1)FresolimumabLerdelimumabMetelimumabLY-2109761Galunisertib (LY-2157299)RepSox (E-616452, SJN-2511)ALK6 (BMPR1B)15 (GDF9B)5 (BMP14)6 (BMP13)7 (BMP12)ALK7 (ACVR1C)TGFβR2ACVR2A (ACVR2)SotaterceptOsteogenin (BMP3, BMP3A)AMHR2 (AMHR)TGFβR3 (β-glycan)Cerberus (CER1)DAN (PARN)Gremlin (Drm)Thrombospondin 1 (THBS1)StamulumabTRC105Endoglinchromosome 10