Bone morphogenetic protein 3
[5] The protein encoded by this gene is a member of the transforming growth factor beta superfamily.It, unlike other bone morphogenetic proteins (BMP's) inhibits the ability of other BMP's to induce bone and cartilage development.BMP3 is an antagonist to other BMP's in the differentiation of osteogenic progenitors.BMP3 is hypermethylated in many cases of colorectal cancer (CRC) and hence along with other hypermethylated genes, may be used as a biomarker to detect early stage CRC.This article on a gene on human chromosome 4 is a stub.