Dermis

Blood vessels in the dermal papillae nourish all hair follicles and bring nutrients and oxygen to the lower layers of epidermal cells.[5] They remain substantially unaltered (except in size) throughout life, and therefore determine the patterns of fingerprints, making them useful in certain functions of personal identification.Because the main function of the dermis is to support the epidermis, this greatly increases the exchange of oxygen, nutrients, and waste products between these two layers.Additionally, the increase in the surface area prevents the dermal and epidermal layers from separating by strengthening the junction between them.It has raised ridges, a thicker and more complex epidermis, increased sensory abilities, and the absence of hair and sebaceous glands.
Illustration of dermal circulation and layers
Anatomical terminologyepidermissubcutaneous tissuesdense irregular connective tissuebasement membranecollagenelastic fibersextrafibrillar matrixmechanoreceptorsthermoreceptorshair folliclessweat glandssebaceous glands (oil glands)apocrine glandslymphatic vesselsblood vesselsfibroblastsmacrophagesmast cellsmatrixstrengthelastinelasticityglycosaminoglycanshyaluronanproteoglycansglycoproteinsrete ridgesareolar connective tissuecapillariesMeissner's corpusclesneurolemmafingerprintsmucous membranesrete pegscollagenouselasticreticular fibersproteinextensibilityroots of the hairsebaceous glandsreceptorsLanger's linesList of cutaneous conditionsSkin and related structuresStratum corneumStratum lucidumStratum granulosumStratum spinosumMalpighian layerStratum basaleBasal keratinocyteLamina lucidaLamina densaPapillaryDermal papillaeReticularSubcutaneous tissuePanniculusPannusPanniculus adiposusPanniculus carnosusMembranous layerLoose connective tissueSuperficial fasciaAdnexaSkin glandsApocrine sweat glandEccrine sweat glandSebaceousRoot sheathOuter root sheathInner root sheathHenle's layerHuxley's layerHair shaftCuticleCortexMedullaBulb with matrix cellsHair follicleMuscleArrector pili musclePilosebaceous unitsebaceous glandNail matrixNail plateLunulaEponychiumParonychiumHyponychiumConnective tissueSoft tissueFibrosisScarringFibroblastFibrocyteReticular cellTendon cellAdipocyteMelanocyteWandering cellsMast cellMacrophageExtracellular matrixGround substanceTissue fluidCollagen fibersCOL3A1FibrillinEMILIN1ElauninProperAdiposeSubmucosaDense regular connective tissueLigamentTendonAponeurosisMucoidMesenchymalCartilageRoutes of administrationdosage formsDigestive tractenteralSolidsTabletCapsulePastilleTime release technologyOsmotic delivery systemLiquidsDecoctionElixirElectuaryEmulsionEffervescent powder or tabletHerbal teaHydrogelMolecular encapsulationPowderSoftgelSolutionSuspensionTinctureOral mucosabuccalsublabialsublingualOrally disintegrating tabletSublingual dropsLozengesEffervescentChewing gumMouthwashToothpasteOintmentRespiratory tractinhalationDry-powder inhalerSmokingAnesthetic vaporizerHeated humidified high-flow therapyMedical inhalantsMetered-dose inhalerNebulizerVaporizerOxygen maskNasal cannulaOxygen concentratorAnaesthetic machineRelative analgesia machineOphthalmicNasal sprayEar dropsEye dropsInsufflationMucoadhesive microdiscUrogenitalPessaryVaginal ringDoucheIntrauterine deviceExtra-amniotic infusionIntravesical infusionRectalSuppositoryMurphy dripNutrient enematopicalTopical creamTopical gelLinimentIontophoresisLiposomesTransfersome vesiclesLotionLip balmMedicated shampooDermal patchTransdermal patchTransdermal sprayJet injectorParenteralsInjectionsinfusionstransdermalIntradermalSubcutaneousInjector penTransdermal implantIntracavernousIntravitrealIntra-articularCentral nervous systemIntrathecalEpiduralCirculatorymusculoskeletalIntravenousIntracardiacIntramuscularIntraosseousIntraperitonealNanocell injectionPatient-controlled analgesiaPIC line