Toxaphene

Exposure to toxaphene has proven to stimulate the central nervous system, as well as induce morphological changes in the thyroid, liver, and kidneys.Exposure to high levels of toxaphene can cause damage to the lungs, nervous system, liver, kidneys, and in extreme cases, may even cause death.The breakdown of usage can be summarized: 85% on cotton, 7% to control insect pests on livestock and poultry, 5% on other field crops, 3% on soybeans, and less than 1% on sorghum.As a result of Environmental Protection Agency restrictions, annual toxaphene usage fell to 6.6 million pounds in 1982.People in the Canadian Arctic, where a traditional diet consists of fish and marine animals, have been shown to consume ten times the accepted daily intake of toxaphene.The major health effects of toxaphene involve central nervous system stimulation leading to convulsive seizures.[8] A study conducted between 1954 and 1972 of male agricultural workers and agronomists exposed to toxaphene and other pesticides showed that there are higher proportions of bronchial carcinoma in the test group than in the unexposed general population.[15] Toxaphene has been found on at least 68 of the 1,699 National Priorities List sites identified by the United States Environmental Protection Agency.Most uses of toxaphene were cancelled in the U.S. in 1982 with the exception of use on livestock in emergency situations, and for controlling insects on banana and pineapple crops in Puerto Rico and the U.S. Virgin Islands.[8] Toxaphene has been banned in 37 countries, including Austria, Belize, Brazil, Costa Rica, Dominican Republic, Egypt, the EU, India, Ireland, Kenya, Korea, Mexico, Panama, Singapore, Thailand and Tonga.Its use has been severely restricted in 11 other countries, including Argentina, Columbia, Dominica, Honduras, Nicaragua, Pakistan, South Africa, Turkey, and Venezuela.The OCPs or pesticide-POPs identified on this list have been termed the "dirty dozen" and include aldrin, chlordane, DDT, dieldrin, endrin, heptachlor, hexachlorobenzene, mirex, and toxaphene.[19] Trade names and synonyms include Chlorinated camphene, Octachlorocamphene, Camphochlor, Agricide Maggot Killer, Alltex, Allotox, Crestoxo, Compound 3956, Estonox, Fasco-Terpene, Geniphene, Hercules 3956, M5055, Melipax, Motox, Penphene, Phenacide, Phenatox, Strobane-T, Toxadust, Toxakil, Vertac 90%, Toxon 63, Attac, Anatox, Royal Brand Bean Tox 82, Cotton Tox MP82, Security Tox-Sol-6, Security Tox-MP cotton spray, Security Motox 63 cotton spray, Agro-Chem Brand Torbidan 28, and Dr Roger's TOXENE.
IUPAC nameCAS NumberChEMBLChemSpiderECHA InfoCardEC NumberPubChemCompTox DashboardSMILESChemical formulaMolar massDensityMelting pointBoiling pointSolubility in waterVapor pressureGHS labellingPictogramsHazard statementsPrecautionary statementsFlash pointstandard stateinsecticidecottonUnited Stateschlorine gascamphene2001 Stockholm Convention on Persistent Organic Pollutantscentral nervous systemthyroidkidneyshumansdrinking waternervous systemcarcinogenorganicchlorinationbicyclicchemical formulasformula weightsaromatic hydrocarbonsaliphatic organic solventspesticidevegetablessoybeansscam miteslivestockstreamsinsectpoultrysorghumEnvironmental Protection AgencyinsolubleCelsiushalf-lifesedimentdechlorinationaerobic conditionsseafoodfatty tissuesoxidationinsolubilityShellfishmarine mammalsCanadian Arcticmarine animalsblubberbeluga whalesArcticseizuresrespiratoryagronomistsbronchialcarcinomaInternational Agency for Research on CancerCaliforniahyperpolarizationNational Priorities ListUnited States Environmental Protection AgencyPuerto RicoU.S. Virgin Islandsaldrinchlordanedieldrinendrinheptachlorhexachlorobenzenemaximum contaminant levelUnited States Food and Drug AdministrationUnited States Department of Transportationhazardousextremely hazardous substanceEmergency Planning and Community Right-to-Know ActNational Institute for Occupational Safety and HealthBibcodeGovernment Printing OfficePest controlInsecticidesCarbamatesAldicarbAminocarbBendiocarbButocarboximCarbarylCarbofuranCarbosulfanm-Cumenyl methylcarbamateEthienocarbFenobucarbMethomylMetolcarbOxamylPromecarbPropoxurInorganic compoundsAluminium phosphideBoric acidChromated copper arsenateCopper(II) arsenateCopper(I) cyanideCryoliteDiatomaceous earthLead hydrogen arsenateParis GreenScheele's GreenInsect growth regulatorsBenzoylureasBistrifluronDiflubenzuronFlufenoxuronLufenuronNoviflumuronHydropreneMethoprenePyriproxyfenNeonicotinoidsAcetamipridClothianidinDinotefuranImidaclopridImidaclothizNitenpyramNithiazinePaichongdingThiaclopridThiamethoxamOrganochloridesBeta-HCHCarbon tetrachlorideCyclodiene1,2-DCB1,4-DCB1,1-DCE1,2-DCEDicofolEndosulfanKeponeLindaneMethoxychlorTetradifonOrganophosphorusAcephateAzamethiphosAzinphos-methylBensulideChlorethoxyfosChlorfenvinphosChlorpyrifosChlorpyrifos-methylCoumaphosDemeton-S-methylDiazinonDichlorvosDicrotophosDiisopropyl fluorophosphateDimefoxDimethoateDioxathionDisulfotonEthionEthopropFenamiphosFenitrothionFenthionIsoxathionMalathionMethamidophosMethidathionMevinphosMipafoxMonocrotophosOmethoateOxydemeton-methylParathionParathion-methylPhenthoatePhoratePhosalonePhosmetPhoximPirimiphos-methylQuinalphosR-16661SchradanTemefosTebupirimfosTerbufosTetrachlorvinphosTrichlorfonPyrethroidsAcrinathrinAllethrinsBifenthrinBioallethrinCyfluthrinCyhalothrinCypermethrinCyphenothrinDeltamethrinEmpenthrinEsfenvalerateEtofenproxFenpropathrinFenvalerateFlumethrinFluvalinateImiprothrinMetofluthrinPermethrinPhenothrinPrallethrinPyrethrinchrysanthemic acidPyrethrumResmethrinSilafluofenTefluthrinTetramethrinTralomethrinTransfluthrinDiamidesChlorantraniliproleCyantraniliproleFlubendiamideAfoxolanerAmitrazAzadirachtinBensultapBuprofezinCartapChlordimeformChlorfenapyrCyromazineFenoxycarbFipronilFluralanerHydramethylnonIndoxacarbLimoneneLotilaner+milbemycin oximePyriproleSarolanerAdjuvantsPiperonyl butoxideSesamexSpinosadSulfluramidTebufenozideTebufenpyradVeracevineXanthoneMetaflumizoneRyanodineMetabolitesMalaoxonParaoxonBiopesticidesBacillus thuringiensisBaculovirusBeauveria bassianaBeauveria brongniartiiIsaria fumosoroseaMetarhizium acridumMetarhizium anisopliaeNomuraea rileyiLecanicillium lecaniiPaenibacillus popilliaePurpureocillium lilacinum