Periostitis
Periostitis, also known as periostalgia, is a medical condition caused by inflammation of the periosteum, a layer of connective tissue that surrounds bone.[1] The condition is generally chronic and is marked by tenderness and swelling of the bone and pain.Acute periostitis is due to infection, characterized by diffuse formation of pus, severe pain, and constitutional symptoms, and usually results in necrosis.Evidence for periostitis found in the fossil record is studied by paleopathologists, specialists in ancient disease and injury.Periostitis has been seen in the late Cretaceous-Eocene crocodile Borealosuchus formidabilis, once known as Leidyosuchus.