HLA-DR2 (DR2) of the HLA-DR serotype system, is a broad antigen serotype that is now preferentially covered by HLA-DR15 and HLA-DR16 serotype group.This serotype primarily recognizes gene products of the HLA-DRB1*15 and HLA-DRB1*16 allele groups.DR2 serotypes are associated with Goodpasture syndrome, systemic lupus erythematosus, multiple sclerosis,[2] narcolepsy, tuberculoid leprosy[3] (multi-drug-resistant tuberculosis or leprosy),[4] ulcerative colitis (Japanese),[5] primary biliary cirrhosis and autoimmune hepatitis.[6] DR2 is also found in all patients that test positive for anti-Asn-RNA-synthetase and chronic interstitial lung disease.[7] DR2 is linked to the HLA-DR51.
