HLA-DRB1

1A6A, 1BX2, 1YMM, 2WBJ,%%s1AQD, 1DLH, 1FYT, 1HXY, 1JWM, 1JWS, 1JWU, 1KG0, 1KLG, 1KLU, 1LO5, 1PYW, 1R5I, 1SEB, 1SJH, 1T5W, 1T5X, 2FSE, 2G9H, 2IAM, 2IAN, 2ICW, 2IPK, 2OJE, 2XN9, 3L6F, 3PDO, 3PGC, 3PGD, 3QXA, 3QXD, 3S4S, 3S5L, 4AEN, 4AH2, 4C56, 4E41, 4FQX, 4GBX, 4I5B, 4OV5, 4X5W, 4X5X,%%s1D5M, 1D5X, 1D5Z, 1D6E, 1J8H, 2SEB, 3O6F, 3T0E, 4IS6, 4MCY, 4MCZ, 4MD0, 4MD4, 4MD5, 4MDI, 4MDJ, 4Y19, 4Y1A312314969ENSG00000228080ENSMUSG00000060586P01911n/aNM_001243965NM_002124NM_001359193NM_001359194NM_010382NP_001230894NP_002115NP_001346122NP_001346123NP_002115.2NP_034512HLA class II histocompatibility antigen, DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene.[6][7] The protein encoded by this gene belongs to the HLA class II beta chain paralogues.The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane.It plays a central role in the immune system by presenting peptides derived from extracellular proteins to T helper cells.Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities.
AliasesHomoloGeneGeneCardsChromosome 6 (human)RNA expressionGene ontologyOrthologsEntrezEnsemblUniProtPubMedWikidataproteinHLA-DRrheumatoid arthritisHLA class IIimmune systemT helper cellsantigen-presenting cellsdomainstransmembranecytoplasmicpolymorphismsallelesanti-IgLON5 diseaseMajor histocompatibility complexMHC class IMHC class IIHLA-DMHLA-DOHLA-DPHLA-DQHuman leukocyte antigenMinor histocompatibility antigenBlood transfusionArrestinCalgranulinHuman blood group systemsCell adhesion moleculesCluster of differentiationchromosome 6