[medical citation needed] For the average woman, the U.S. Preventive Services Task Force recommended (as of 2009[update]) mammography every two years in women between the ages of 50 and 74.[15] Presently, Cochrane Collaboration recommends that women should at least be informed of the benefits and harms of mammography screening and have written an evidence-based leaflet in several languages that can be found on www.cochrane.dk.[22] since it is able to overcome the primary limitation of standard 2D mammography which had a masking effect due to the overlapping fibroglandular tissue, whereas DBT is able to distinguish between benign and malignant features, particularly in dense breasts.[23] DBT has also been found to be a reliable tool for intraoperative surgical margin assessment in non-palpable lesions thus reducing the volume of breast excision without increasing the risk of cancer recurrence.[24] No longer in widespread use, xeromammography is a photoelectric method of recording an x-ray image on a coated metal plate, using low-energy photon beams, long exposure time, and dry chemical developers.In a study published by Schulz-Wendtland R et al., investigators made more mistakes when using only ductal sonography compared to when they used contrast-enhanced galactography with tomosynthesis which allowed for generated synthetic digital 2D full-field mammograms to diagnose suspicious lesions.The available literature suggests that the sensitivity of contrast-enhanced breast MRI in detection of cancer is considerably higher than that of either radiographic mammography or ultrasound and is generally reported to be in excess of 94%.[36] Additionally, MRI Is also shown to be more accurate than mammography, ultrasound, or clinical exam in evaluating treatment response to neoadjuvant therapy.[40] Recent studies have shown that shear wave elastography in primary invasive breast carcinoma could be useful for indicating axillary lymphadenopathy.A recent study found 100% ultrasound localization with negative margins obtained in both non-palpable and palpable lesions at initial procedure.Additionally, the combined use of MRI and CEUS in lesions > 20 mm has been shown to optimize the diagnostic specificity and accuracy in breast cancer prediction.[44] Research has also shown that Tc-99 Sestamibi wash out rate is a reliable test for predicting tumor response to neoadjuvant chemotherapy in locally advanced breast cancer.
The best mammographic images are produced with compression which reduces radiation needed and spreads tissue to produce clearer images.
A color-enhanced MRI of a breast
Breast ultrasounds may be used with or without a mammogram.