It is a neo-classical building, originally constructed from locally quarried, red Collyhurst sandstone although, due to its soft nature, much of the original stone has since been replaced with sandstone of various colours from Parbold in Lancashire, Hollington in Staffordshire, Darley Dale in Derbyshire and Runcorn in Cheshire.[a] The furniture includes a Queen Anne altar table, thought to be the only existing one of its kind, and a painting of "The Descent from the Cross" by Annibale Carracci of Bologna, which had previously hung in the nearby St Peter's Church prior to is demolition in 1907.Lady Bland herself is buried in the Church of St James, Didsbury, where a memorial plaque commemorates her life.One of those who did so was John Byrom (1692–1763), author of Christians Awake, who played quite a prominent part at St Ann's under the first two rectors, despite his Jacobite sympathies.In 1975, the Friends of St Ann's Church was formed from the business houses in the parish, to maintain the fabric of this historic building.[12] During renovation work the church was draped in large advertising banners, which was controversial for a Grade I listed building.