Periplocin

Periplocin is a plant-derived glycoside whereby the sugar moiety is linked to a steroid.[2][3] CPP's healing activities have long been recognized in traditional Chinese medicine[3] where it has been used to treat rheumatoid arthritis.[2] Scientific studies of CPP have identified over 100 components of which periplocin has been a major focus both for its toxicity as well as for its potential beneficial pharmaceutical effects.[2] Besides the cardiac glycosides with periplocin as its main constituent, the CPP contains different C21-steroidal glycosides such as periplocodides and pregnene derivatives, fatty acids, volatile oils, terpenes, and others.Potential senolytic activity was suggested by an AI structural analysis of over 4,000 chemicals in 2013.