Myoglobin
Although its heme group is identical to those in Hb, Mb has a higher affinity for oxygen than does hemoglobin but fewer total oxygen-storage capacities.If meat has been exposed to nitrites, it will remain pink, because the iron atom is bound to NO, nitric oxide (true of, e.g., corned beef or cured hams).Grilled meats can also take on a reddish pink "smoke ring" that comes from the heme center binding to carbon monoxide.[23] Raw meat packed in a carbon monoxide atmosphere also shows this same pink "smoke ring" due to the same principles.Impossible Foods uses leghemoglobin, a heme-containing globin from soy root nodule, produced as a recombinant protein in Komagataella ("Pichia pastoris") yeast.[29] Moolec Science has engineered a soybean that produces porcine myoglobin in its seeds called "Piggy Sooy"; it was approved by the USDA in April 2024.[33] However, elevated myoglobin has low specificity for acute myocardial infarction (AMI) and thus CK-MB, cardiac troponin, ECG, and clinical signs should be taken into account to make the diagnosis.[citation needed] Many models of myoglobin have been synthesized as part of a broad interest in transition metal dioxygen complexes.
AliasesHomoloGeneGeneCardsChromosome 22 (human)RNA expressionGene ontologyOrthologsEntrezEnsemblUniProtPubMedWikidataoxygenproteinskeletalmuscle tissuehemoglobincooperative bindingmuscle injurysmooth muscleX-ray crystallographyJohn KendrewNobel Prize in chemistryMax Perutzreactive oxygen speciesmetmyoglobincarboxyhemoglobinmethemoglobinpigmentsred meatbound to an oxygen moleculewell donenitritesnitric oxidecorned beefcarbon monoxideHormelCargillMeat alternativesImpossible Foodsleghemoglobinroot nodulerecombinant proteinKomagataellasoybeanrhabdomyolysiskidneysacute kidney injuryprotoxinlysosomesheart attackchest painspecificityacute myocardial infarction (AMI)cardiac troponinglobinalpha helicesporphyrinhistidinehigh spindiamagnetictransition metal dioxygen complexestetraphenylporphyrinimidazoledioxygenCytoglobinHemoproteinNeuroglobinPhytoglobinMyoglobinuriaIschemia-reperfusion injury of the appendicular musculoskeletal systemcytosolrenal insufficiencyrenal diseaseBibcodeForbestroponin IOnline Mendelian Inheritance in ManPDBe-KBProteinshemoproteinsGlobinspseudoBeta locusTetramersHbE Gower 1HbE Gower 2HbE Portland IHbE Portland IIHbF/FetalCarbaminohemoglobinOxyhemoglobinDeoxyhemoglobinSulfhemoglobinGlycated hemoglobinChlorocruorinErythrocruorinCytochromeCytochrome bCytochrome P450Methemalbuminblood testsElectrolytesSodiumPotassiumChlorideCalciumRenal functionCreatinineBUN-to-creatinine ratioPlasma osmolalitySerum osmolal gapAcid-baseAnion gapArterial blood gasBase excessBicarbonateCO2 contentIron testsFerritinSerum ironTransferrin saturationTotal iron-binding capacityTransferrinTransferrin receptorHormones