Microarray

It is a two-dimensional array on a solid substrate—usually a glass slide or silicon thin-film cell—that assays (tests) large amounts of biological material using high-throughput screening miniaturized, multiplexed and parallel processing and detection methods.[3][4][5] The "gene chip" industry started to grow significantly after the 1995 Science Magazine article by the Ron Davis and Pat Brown labs at Stanford University.The basic principle of the microarray is the printing of small stains of solutions containing different species of the probe on a slide several thousand times.Ongoing efforts to advance microarray technology aim to create uniform, dense arrays while reducing the necessary volume of solution and minimizing contamination or damage.Modern approaches do not include just DNA as a sample anymore, but also proteins, antibodies, antigens, glycans, cell lysates and other small molecules.With this method high-quality custom arrays can be produced with a very high density of DNA features by using a compact device with few moving parts.
A Venn diagram outlining and contrasting some aspects of the fields of bio-MEMS , lab-on-a-chip , μTAS .
Microarrays (journal)Venn diagrambio-MEMSlab-on-a-chipμTAS multiplexsolid substrateglass slidesilicon thin-film cellassaysbiological materialhigh-throughput screeningantibody microarraysantibody matrixTse Wen Changgene chipScience MagazineAffymetrixAgilentIlluminaDNA microarraysMMChipsProtein microarraysPeptide microarraysprotein–protein interactionsTissue microarraysCellular microarraysChemical compound microarraysGlycan arraysPhenotype microarraysReverse phase protein lysate microarraysmagnetic nanoparticlesnuclear magnetic resonancelithographyUV lightPhotochemistryMicroarray databasesMicroarray analysis techniquesDNA MicroarrayBiochipBibcodeCiteSeerX