Matson is an unincorporated community in southern St. Charles County, Missouri, United States.[1] It is located approximately three miles south of Defiance on Route 94 and is near the Missouri River.A post office called Matson was established in 1893, and remained in operation until 1971.[2] The community most likely has the name of Abraham Matson, a pioneer citizen.This St. Charles County, Missouri state location article is a stub.