She is regarded to be the first woman to receive a Doctor of Philosophy in Spain.She was given an unusually good education and described as the child prodigy of the king.She was given special royal dispensation from Charles III of Spain to study at the humanistic and literary faculty of the University of Alcalá, where she graduated in 1785 as a Doctor of Philosophy.She was named honorary professor of philosophy at the university and called Doctora de Alcalá.In 1789, she married Alfonso de Sousa, 12th Marquis of Guadalcázar, Grandee of Spain.
