[11][12] Makhachev's father grew tomatoes and worked as a driver; his mother was a housewife and ran a small cafe.He trained in freestyle wrestling for a year but switched to mixed martial arts under Abdulmanap Nurmagomedov after learning that Khabib was already a professional.[19] Makhachev made his M-1 Global debut against Tengiz Khuchua on 12 February 2011 and won the fight via KO in the first round.[21] Makhachev faced then-undefeated Brazilian jiu-jitsu black belt[22] Rander Junio on 21 August 2013 at M-1 Challenge 41.[24] On 7 September 2014, in his final bout for M-1 Global before signing with the UFC, Makhachev defeated Ivica Truscek via submission in the third round.[30] After the weigh-ins, the UFC announced that the bout was cancelled after Makhachev failed an out-of-competition drug screening, testing positive for the banned anti-ischemic meldonium.[31] USADA lifted Makhachev's suspension after a hearing on 2 July 2016 determined that the drug was prescribed in November 2015 to recover from a medical procedure to his heart.[38] However, Makhachev pulled out of the fight in the beginning of August citing a religious reason, and he was replaced by Mads Burnell.[44] However, it was reported on 11 November 2018 Makhachev was pulled out from the event due to undisclosed reason and he was replaced by Alexander Hernandez.[52] However, Makhachev was removed from the card due to travel restrictions related to the COVID-19 pandemic and he was replaced by Omar Morales.[67] However, on 12 February 2022 it was reported that Dariush withdrew from the event due to an ankle injury[68] and he was replaced by Bobby Green.[72] Makhachev won the bout and the title in the second round via arm-triangle choke after knocking down Oliveira with a punch.[79][80] Makhachev was scheduled to make his second title defense in a rematch against Charles Oliveira on 21 October 2023, at UFC 294.