Heteroatom
In chemistry, a heteroatom (from Ancient Greek heterosĀ 'different' and atomosĀ 'uncut') is, strictly, any atom that is not carbon or hydrogen.[1] In practice, the term is mainly used more specifically to indicate that non-carbon atoms have replaced carbon in the backbone of the molecular structure.Typical heteroatoms are nitrogen (N), oxygen (O), sulfur (S), phosphorus (P), chlorine (Cl), bromine (Br), and iodine (I),[2][3] as well as the metals lithium (Li) and magnesium (Mg).In the description of protein structure, in particular in the Protein Data Bank file format, a heteroatom record (HETATM) describes an atom as belonging to a small molecule cofactor rather than being part of a biopolymer chain.[4] In the context of zeolites, the term heteroatom refers to partial isomorphous substitution of the typical framework atoms (silicon, aluminium, and phosphorus) by other elements such as beryllium, vanadium, and chromium.