Harlem Avenue is a major north–south street located in Chicago and its west, southwest, and northwest suburbs.It stretches from Glenview Road in Glenview to the intersection of East South Street and South Drecksler Road in Peotone, where it diverges into Illinois Route 50.An express bus service from Pace Pulse is currently being planned for the portion of the street between 95th Street and North Avenue, serving primarily the southern and western suburbs.[1] From north to south: As one of the most important thoroughfares in Chicagoland outside of Downtown Chicago, Harlem Avenue offers a number of transit connections to the Chicago Loop and points west.Two of Amtrak's secondary Chicagoland stations are also located along Harlem Avenue, serving the two most popular Midwest passenger services (Hiawatha between Chicago and Milwaukee and Lincoln between Chicago and St. Louis) as well as three long-distance routes.