Generalized granuloma annulare
Generalized granuloma annulare is a skin condition of unknown cause, tending to affect women in the fifth and sixth decades, presenting as a diffuse but symmetrical, papular or annular eruption of more than ten skin lesions, and often hundreds.[3] A variety of factors, such as infection, sun exposure, medication use, and trauma, appear to play a role in the development of the disease.[4] It has been observed that certain laboratory abnormalities exist, such as hyperlipidemia, hypergammaglobulinemia, and the presence of circulating antinuclear antibodies.[5] Histopathologic analysis may show lymphohistiocytic granuloma-related alterations primarily in the papillary and mid dermis.[4] Generalized granuloma annulare is mostly treated with phototherapy as opposed to oral steroids, however treatment efficacy is constrained by a high rate of recurrence after stopping treatment.