In Lindenau bei Heiligenbeil on 20 August 1803 Frederick Ferdinand married Princess Maria Dorothea Henriette Louise of Schleswig-Holstein-Sonderburg-Beck (28 September 1783, Lindenau – 24 November 1803, Pless), daughter of Friedrich Karl Ludwig, Duke of Schleswig-Holstein-Sonderburg-Beck, and by birth a princess of Denmark as a descendant in the male line of King Christian III.After the Battle of Jena, he commanded his own regiment at Zehdenick near the enemy lines, but was forced to withdraw to Bohemia in order to ensure the disarmament of the Austrians.When the young Duke Louis Augustus died without direct heirs in 1818, Frederick Ferdinand, as his closest male relative, succeeded him in the sovereign duchy.By 1828 he founded a colony in southern Ukraine called "Askania-Nova" (New Ascania), located in the steppes of Tauri, in the northern peninsula of Crimea.Under his government, Bandhauer also built (between 1823 and 1828) the Ferdinandsbau in Schloss Köthen, the monastery and hospital of the Brothers of Mercy (German: Barmherzigen Brüder) in 1829, and the Catholic Church of St. Mary (Kirche St. Maria) in 1830, in the crypt of which Frederick Ferdinand was buried shortly thereafter.