Dornase alfa
Dornase alfa, sold under the brand name Pulmozyme, is used for the treatment of cystic fibrosis.[3] It is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA.[3] Dornase alfa hydrolyzes the DNA present in sputum/mucus and reduces viscosity in the lungs, promoting improved clearance of secretions.[3] Dornase alfa is indicated for the management of people with cystic fibrosis to improve pulmonary function.[4] Dornase alfa has been shown to improve lung function in non-cystic fibrosis pre-term infants atelectasis.