Dennis Kasper

He was also executive dean for academic programs at Harvard Medical School and director of the Channing Laboratory Department of Medicine at Brigham and Women's Hospital.His primary focus is on immunochemistry alongside the genetics of bacteria and their role in virulence – research that has concentrated on topics related to bacterial polysaccharides and glycolipids.[2] Kasper is also known as editor (alongside Anthony Fauci, Stephen L. Hauser and others) of Harrison's Principles of Internal Medicine – a book widely used by medical schools and practicing physicians.[6] He was also the scientific director at the New England Center of Excellence in Biodefense and Emerging Infectious Diseases at Harvard Medical School until 2014.Kasper's research in the space of sphingolipids led his group to discover B. fragilis glycosphingolipids, which modulate natural killer T cell mediated inflammation in the colon; this alongside the polysaccharide A work were the first immunomodulatory molecules identified from the microbiome.
National Academy of MedicineNational Academy of SciencesAlbany Prize for Biomedical ResearchPaul Ehrlich and Ludwig Darmstaedter PrizeMicrobiologyimmunologyWilliam Ellery ChanningHarvard Medical Schoolexecutive deanBrigham and Women's Hospitalimmunochemistrybacterial polysaccharidesglycolipidsAnthony FauciStephen L. HauserChicago, Illinoisfirst-generation AmericanUniversity of Illinois, Urbanapre-medzoologyUniversity of Illinois College of Medicine, ChicagoNew York HospitalPeter Bent Brigham HospitalWalter Reed Army Institute of ResearchChanning Laboratory at Brigham and Women's HospitalNational Science Advisory Board of BiosecurityNational Institute of Allergy and Infectious Diseasesmicrobiotaimmunomodulatorycapsular polysaccharidesB Streptococcus (GBS)GBS infectionserotypesBacteroides fragilisgut microbiotaimmune systempolysaccharide Ahygiene hypothesissphingolipidsBibcode