CCR8 (gene)

123712776ENSG00000179934ENSMUSG00000042262P51685P56484NM_005201NM_007720NP_005192NP_031746Chemokine (C-C motif) receptor 8, also known as CCR8, is a protein which in humans is encoded by the CCR8 gene.Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites.[7] Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis.More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues.This article incorporates text from the United States National Library of Medicine, which is in the public domain.
AliasesHomoloGeneGeneCardsChromosome 3 (human)RNA expressionGene ontologyOrthologsEntrezEnsemblUniProtPubMedWikidataproteincluster of differentiationchemokine receptorthymusthymic cellapoptosisT cellsCC chemokine receptorsUCSC Genome BrowserUnited States National Library of Medicinepublic domainCytokine receptorsCX3CR1CMKLR1TNF receptorFas receptorOsteoprotegerinTweakRTAJ/TROYJAK-STATType Iγ-chainInterleukin receptorsIL13RA1IL13RA2β-chainGM-CSFIL11RAIL27RAIL12RB1IL12RB2CSF receptorsThrombopoietinhormone receptorprolactinType IIIL10RAIL10RBIL22RA1IL22RA2IL20RAIL20RBInterferon receptors-α/βIFNAR1IFNAR2IFNGR1IFNGR2Ig superfamilyIL18R1IL 17 familyIL17RAIL17RBIL17RCIL17RDEnzyme-linked receptorSer/ThrTGF-betaTGFBR1TGFBR2familyProteinsclusters of differentiationlist of human clusters of differentiationCD140bCDw199CD202bCD240CECD240D CD252CDw293CD300AmodulatorsCCL4 (MIP-1β)CCL5 (RANTES)CCL9 (CCL10)Cenicriviroc (TAK-652, TBR-652)CCL3 (MIP-1α)MogamulizumabAplavirocMaravirocVicrivirocPRO-140BertilimumabCarlumabCXCR1(IL-8Rα)Interleukin-8 (CXCL8, GCP-1)CXCR2(IL-8Rβ)CXCL1 (MGSA)CXCL4 (PF4)CXCL9 (MIG)CXCL10 (IP-10)CXCL11 (I-TAC)EldelumabSDF-1 (CXCL12)UbiquitinMavorixaforPlerixafor (AMD3100)UlocuplumabCXCL13CXCL16ConolidineLIH383RTI-5152-12C (XC)Lymphotactin-α (XCL1)Lymphotactin-β (XCL2)PateclizumabFractalkine (CX3CL1)CC (β) chemokinesChemerintransmembrane receptor