Biopanning

This involves inserting foreign desired gene segments into a region of the bacteriophage genome, so that the peptide product will be displayed on the surface of the bacteriophage virion.It utilizes the binding interactions so that only specific peptides presented by bacteriophage are bound to the target.For example, selecting antibody presented by bacteriophage with coated antigen in microtiter plates.The end result is the peptides produced by bacteriophage are specific.The cycle can occur many times resulting with strong affinity binding peptides to the target.
peptidestargetantibodiesphage displaybacteriophagebacteriophage M13antigengram-negativeJournal of theoretical biologyMethods in Enzymology